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Skin Rash & Itching (Pruritus)

Medically Reviewed & Fact-CheckedBy MD, Emergency Medicine & Internal Medicine
Reviewed: 9/6/2026

Overview

An inflammatory reaction of the epidermis and dermis causing visible erythema, papules, plaques, vesicles, or urticarial wheals, often accompanied by intense pruritus.

Possible Causes

  • Allergic Contact Dermatitis (Poison ivy, nickel, cosmetics)
  • Atopic Dermatitis (Eczema)
  • Urticaria (Hives) - IgE-mediated or physical triggers
  • Psoriasis vulgaris
  • Viral exanthems (Measles, Rubella, Varicella, Parvovirus B19)
  • Drug-induced cutaneous adverse reactions (DRESS, SJS/TEN)

When to Seek Care

Seek emergency care if a rash is accompanied by facial swelling, lip swelling, difficulty breathing, or if the skin is blistering and peeling off. Consult a dermatologist for non-urgent chronic itchy rashes.

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