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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Rivaroxaban
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Reduction of risk of stroke and systemic embolism in nonvalvular atrial fibrillation; treatment of DVT and PE.
Deep Vein Thrombosis, Pulmonary Embolism, Nonvalvular Atrial Fibrillation
20 mg orally once daily with the evening meal for AFib; 15 mg twice daily with food for 21 days for acute DVT/PE followed by 20 mg once daily.
Specialized weight-based dosing for pediatric venous thromboembolism.
No adjustment needed based purely on age; dose according to renal clearance.
20 mg daily.
Avoid if CrCl <15 mL/min. Reduce to 15 mg daily for AFib if CrCl 15-50 mL/min.
Avoid in patients with moderate to severe hepatic impairment (Child-Pugh B and C).
Bleeding complications (epistaxis, hematoma, hematuria), abdominal pain, dizziness.
Epidural/spinal hematoma, intracranial hemorrhage, fatal bleeding.
Active pathological bleeding, significant hypersensitivity.
Black Box Warning: Premature discontinuation increases thrombotic event risk; epidural anesthesia risk.
Combined P-gp and strong CYP3A4 inhibitors (ketoconazole, ritonavir) or inducers (rifampin, carbamazepine).
15 mg and 20 mg tablets MUST be taken with food to ensure adequate bioavailability.
Moderate to heavy drinking increases bleeding danger.
Avoid during pregnancy due to intrinsic bleeding hazard for mother and fetus.
Excreted in milk; decide between nursing or medication continuation.
Always take with your evening meal. Report any signs of internal bleeding or black stools.
Take as soon as remembered on the same day. Do not double doses.
Renal function tests, complete blood count, signs of bleeding.
Content for Xarelto was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.