Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescription OnlyClass: Anticholinergics / Antimuscarinics

Tolterodine

Generic Name: Tolterodine

Common Brand Names: Detrol, Detrol LA
Dosage Form:Tablet, Extended-Release Capsule
Route:Oral
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency

Medical Conditions Treated:

Overactive bladder (OAB)

Dosage & Administration Guidelines

Adult Dosage

2 mg twice daily (IR) or 4 mg once daily (ER)

Pediatric Dosage

Not recommended

Elderly / Geriatric Considerations

No initial adjustment; consider lower dose if sensitive

Maximum Dose Limit

4 mg/day

Renal Impairment:

Reduce to 1 mg twice daily (IR) or 2 mg once daily (ER) in severe impairment

Hepatic Impairment:

Reduce to 1 mg twice daily (IR) or 2 mg once daily (ER) in mild to moderate impairment

Side Effects & Safety Warnings

Common Side Effects

Dry mouth, headache, constipation, dry eyes

Serious Adverse Reactions

Urinary retention, QT prolongation, anaphylaxis

Contraindications:

Urinary retention, gastric retention, uncontrolled narrow-angle glaucoma

Important Warnings & Precautions:

May cause CNS effects like somnolence or confusion

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Strong CYP3A4 inhibitors, other anticholinergics

Food & Dietary Interactions:

N/A

Alcohol Interaction Warning:

May enhance CNS depression

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use only if benefit outweighs risk

Breastfeeding / Lactation

Not recommended

Patient Counseling & Practical Advice

How to Take:

May cause blurred vision or dizziness. Sip water or use hard candy for dry mouth.

What to Do if You Miss a Dose:

Skip the missed dose and resume at next scheduled time.

Recommended Monitoring & Lab Tests:

Urinary symptoms, post-void residual

Trustworthy Sources & Medical Review

Content for Tolterodine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.