Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescription OnlyClass: Phosphodiesterase-5 Inhibitors

Tadalafil

Generic Name: Tadalafil

Common Brand Names: Cialis, Adcirca
Dosage Form:Tablet
Route:Oral
Pregnancy Category:B
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Treatment of erectile dysfunction, benign prostatic hyperplasia

Medical Conditions Treated:

Erectile dysfunction (ED), BPH, Pulmonary arterial hypertension (PAH)

Dosage & Administration Guidelines

Adult Dosage

10 mg as needed for ED; 5 mg daily for BPH

Pediatric Dosage

Not recommended

Elderly / Geriatric Considerations

Consider lower starting dose

Maximum Dose Limit

20 mg/day for ED; 40 mg/day for PAH

Renal Impairment:

Max 5 mg/day if severe impairment

Hepatic Impairment:

Max 10 mg as needed if mild/moderate; avoid in severe

Side Effects & Safety Warnings

Common Side Effects

Headache, dyspepsia, back pain, myalgia

Serious Adverse Reactions

Priapism, sudden vision loss, sudden hearing loss

Contraindications:

Concurrent use of nitrates or guanylate cyclase stimulators

Important Warnings & Precautions:

Cardiovascular risk, potential for prolonged erection

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Nitrates, alpha-blockers, antihypertensives, CYP3A4 inhibitors

Food & Dietary Interactions:

Grapefruit juice may increase exposure

Alcohol Interaction Warning:

May increase risk of orthostatic hypotension

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Not indicated for use in females (unless PAH)

Breastfeeding / Lactation

N/A

Patient Counseling & Practical Advice

How to Take:

Seek immediate medical help if erection lasts >4 hours

What to Do if You Miss a Dose:

Take as soon as remembered, but do not take more than one dose daily

Recommended Monitoring & Lab Tests:

Blood pressure, heart rate

Trustworthy Sources & Medical Review

Content for Tadalafil was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.