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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Tacrolimus
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Prophylaxis of organ rejection
Organ transplant rejection, Atopic dermatitis
0.1-0.2 mg/kg/day orally in two divided doses
0.15-0.3 mg/kg/day orally in two divided doses
Use lower end of adult dosage range
Based on target trough concentrations
Use lowest recommended dose
Reduce dose in severe impairment
Tremor, headache, diarrhea, hypertension, nausea
Nephrotoxicity, neurotoxicity, increased risk of infections
Hypersensitivity to tacrolimus
Increased risk of malignancies and infections
CYP3A inhibitors/inducers
Grapefruit juice increases levels
May increase side effects
Use only if benefit justifies risk
Present in milk, avoid
Take consistently with/without food, avoid grapefruit
Take as soon as remembered if within 14 hours
Whole blood trough concentrations, renal function
Content for Tacrolimus was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.