Nitroglycerin
Generic Name: Nitroglycerin
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Acute relief or prophylaxis of angina pectoris
Angina Pectoris, Anal Fissure (Topical)
Dosage & Administration Guidelines
0.4 mg SL every 5 minutes up to 3 doses for acute angina
N/A
Same as adult; start low due to risk of hypotension
3 tablets in 15 minutes
No adjustment necessary
No adjustment necessary
Side Effects & Safety Warnings
Headache, dizziness, lightheadedness, nausea, flushing
Severe hypotension, syncope, reflex tachycardia
Use of PDE-5 inhibitors (sildenafil, tadalafil), severe anemia, elevated ICP
Risk of tolerance without a 10-12 hour nitrate-free interval
Interactions (Drugs, Food & Alcohol)
PDE-5 inhibitors, riociguat, antihypertensives
N/A
Increases risk of severe hypotension
Pregnancy & Breastfeeding Safety
Use only if clearly needed
Use caution; excretion in milk unknown
Patient Counseling & Practical Advice
Sit down before taking. If pain persists after first dose, call 911 immediately.
If scheduled, take as soon as remembered. Do not double doses.
Blood pressure, heart rate, angina frequency
Content for Nitroglycerin was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.