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Medically Verified MonographPrescription OnlyClass: Alpha/Beta Adrenergic Blocker

Labetalol

Generic Name: Labetalol

Common Brand Names: Trandate
Dosage Form:Tablet, Injection
Route:Oral, IV
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Hypertension, hypertensive emergencies

Medical Conditions Treated:

High blood pressure

Dosage & Administration Guidelines

Adult Dosage

100 mg twice daily orally

Pediatric Dosage

1-3 mg/kg/day divided twice daily

Elderly / Geriatric Considerations

Start low

Maximum Dose Limit

2400 mg/day orally

Renal Impairment:

N/A

Hepatic Impairment:

Use with caution

Side Effects & Safety Warnings

Common Side Effects

Dizziness, fatigue, orthostatic hypotension

Serious Adverse Reactions

Hepatotoxicity, bronchospasm, heart block

Contraindications:

Asthma, severe bradycardia, cardiogenic shock

Important Warnings & Precautions:

May mask signs of hypoglycemia

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Calcium channel blockers, cimetidine

Food & Dietary Interactions:

Food may increase bioavailability

Alcohol Interaction Warning:

Increases risk of hypotension

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Often used for pregnancy-induced hypertension

Breastfeeding / Lactation

Compatible

Patient Counseling & Practical Advice

How to Take:

Do not stop abruptly, change positions slowly

What to Do if You Miss a Dose:

Take as soon as remembered

Recommended Monitoring & Lab Tests:

Blood pressure, heart rate

Trustworthy Sources & Medical Review

Content for Labetalol was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.