Jardiance
Generic Name: Empagliflozin
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Improve glycemic control in type 2 diabetes; reduce risk of cardiovascular death and hospitalization in adults with heart failure.
Type 2 Diabetes, Heart Failure, Chronic Kidney Disease
Dosage & Administration Guidelines
10 mg orally once daily in the morning; may increase to 25 mg once daily.
Safety not established in pediatric patients.
No specific adjustment, but monitor for volume depletion.
25 mg daily.
Contraindicated on dialysis; dose adjustment not needed if eGFR >= 20 mL/min for heart failure/CKD indications.
No adjustment in mild/moderate hepatic impairment.
Side Effects & Safety Warnings
Urinary tract infections, mycotic genital infections, increased urination.
Ketoacidosis, urosepsis, necrotizing fasciitis of perineum (Fournier gangrene), hypotension.
Severe hypersensitivity to empagliflozin, patients on dialysis.
Assess for ketoacidosis in symptomatic patients; temporary discontinuation before surgery.
Interactions (Drugs, Food & Alcohol)
Diuretics (increased risk of hypotension), insulin secretagogues.
Can be taken with or without food.
Heavy drinking increases ketoacidosis risk.
Pregnancy & Breastfeeding Safety
Not recommended during second and third trimesters.
Not recommended due to potential for serious adverse reactions in infant kidney development.
Patient Counseling & Practical Advice
Stay well-hydrated throughout the day and practice good personal hygiene.
Take it when remembered, but never take two doses on the same day.
Blood pressure, renal function, signs of genital/urinary infection.
Content for Jardiance was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.