Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographOTCClass: Expectorant

Guaifenesin

Generic Name: Guaifenesin

Common Brand Names: Mucinex, Robitussin
Dosage Form:Tablet, Syrup, Liquid
Route:Oral
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Help loosen phlegm and thin bronchial secretions

Medical Conditions Treated:

Chest congestion, cough

Dosage & Administration Guidelines

Adult Dosage

200-400 mg every 4 hours

Pediatric Dosage

100-200 mg every 4 hours (ages 6-12)

Elderly / Geriatric Considerations

Same as adult

Maximum Dose Limit

2400 mg/day

Renal Impairment:

N/A

Hepatic Impairment:

N/A

Side Effects & Safety Warnings

Common Side Effects

Nausea, vomiting, dizziness

Serious Adverse Reactions

N/A

Contraindications:

Hypersensitivity

Important Warnings & Precautions:

Not for persistent coughs like those with smoking, asthma, or emphysema

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

None significant

Food & Dietary Interactions:

N/A

Alcohol Interaction Warning:

N/A

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use if benefit outweighs risk

Breastfeeding / Lactation

Safety not known

Patient Counseling & Practical Advice

How to Take:

Drink plenty of water

What to Do if You Miss a Dose:

Take as soon as remembered

Recommended Monitoring & Lab Tests:

Symptom improvement

Trustworthy Sources & Medical Review

Content for Guaifenesin was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.