Duloxetine
Generic Name: Duloxetine
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Treat depression, anxiety, nerve pain
MDD, GAD, Neuropathic pain, Fibromyalgia
Dosage & Administration Guidelines
30-60 mg daily
Approved for GAD (>=7 yrs)
Start low
120 mg/day
Avoid if CrCl < 30
Avoid in hepatic impairment
Side Effects & Safety Warnings
Nausea, dry mouth, somnolence
Hepatotoxicity, suicidal thoughts
MAOI use, uncontrolled narrow-angle glaucoma
Risk of suicidality in children/young adults
Interactions (Drugs, Food & Alcohol)
MAOIs, SSRIs, CYP1A2 inhibitors
N/A
Heavy alcohol use increases liver injury risk
Pregnancy & Breastfeeding Safety
Risk of neonatal complications
Use caution
Patient Counseling & Practical Advice
Swallow whole, do not crush or chew
Skip missed dose
Mood changes, blood pressure
Content for Duloxetine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.